Improved cancer diagnostics and therapeutics will require targeting ligands with relatively high specificity for the surface of malignant cells compared to normal cells. However, the...
We used the Difference Evolutionary Trace (difference-ET) and residue-swapping to uncover two distinct sets of specificity-determining sequence positions in D2 dopamine receptors and 5HT2AR serotonin...
Several types of cancers, such as ovarian, breast, lung and others, have been linked to the dysfunction of a particular family of cellular receptors (called...
There is a major ongoing research effort to identify oligonucleotide and protein biomarkers of disease. While the use of phospholipid biomarkers are less common, there...
Mechanism of action of VEGF (vascular endothelial growth factor) and EGFR (epidermal growth factor receptor) signalling pathways. Mécanisme d'action des voies de signalisation du VEGF...
Lecture by Kevin Ahern of Oregon State University discussing Biochemistry Basics in BB 450. See the full course at oregonstate.edu This course can be taken...
Protein Lounge animations @ www.proteinlounge.com Apoptosis is a cell suicide mechanism that enables metazoans to control cell number in tissues and to eliminate individual cells...
S-adenosylhomocysteine hydrolase (SAHH), a cellular enzyme that plays a key role in methylation reactions including those required for maturation of viral mRNA, is an important...
S-adenosylhomocysteine hydrolase (SAHH), a cellular enzyme that plays a key role in methylation reactions including those required for maturation of viral mRNA, is an important...
